September 2-7, 2011, Spetses, Greece

Dear Participants of the 3rd FEBS-MPST 2011 Advanced Lecture Course,

Dear Colleagues and Friends,

On behalf of the organizing committee, I would like to express my sincere gratitude for your active participation in the scientific sessions and social events of the 3rd FEBS Advanced Lecture Course “Matrix Pathobiology, Signaling and Molecular Targets”, held at the “Anargyrios & Korgialenios School of Spetses” and Spetses Hotel, 2-7 September 2011.

The scientific sessions, which included invited lectures, selected talks, poster presentations/panel discussions and speakers’ corners, thanks to your very active participation and interest, were all superb. Moreover, the social events created a very friendly atmosphere for interactions between the participants as well as the young scientists with the outstanding experts.

The success of this meeting inaugurates forthcoming events in this scientific field and I would be grateful you’re joining us in future events.

Nikos Karamanos


Dear Colleagues and Friends,

On behalf of the Organizing Committee, it is a pleasure to invite you to the 3rd FEBS-MPST Advanced Lecture Course, which follows the previous successful FEBS-MPST 2009 and 2007 meetings.

Based on the great advances occurred during the last years in the field of matrix pathobiology and the increasing research interest on matrix organization and the matrix-mediated regulation of the various cell functions, the FEBS-MPST 2011 will offer oral sessions with invited plenary lectures, general lectures/tutorials, selected short talks related to the topics of the presented abstracts, participant poster presentations, panel discussions and speakers’ corner. These sessions will address both basic and applied science topics that appeal to the range of participants working in the fields of matrix Pathobiology and Pathobiochemistry, structural biology and cell and molecular biology.

The organizing committee has put together an outstanding group of internationally recognised speakers. The lectures and tutorials will provide you with an update important new knowledge covering key areas of the field. The most important goal of this course is to bring together scientists from biochemistry, life sciences and molecular cell biology on an important and rapidly developing scientific field and to create the environment for a superb science, warm collegiality, and an all-around rewarding experience during this special time of year.

We are looking forward to welcome you in Spetses island, Greece for an exciting and memorable scientific meeting.

Nikos Karamanos
Chairman of the Organizing Committee

FEBS J-Minireview Series

Thanks to the contribution of the invited speakers of the FEBS-MPST Advanced Lecture Courses, the following MiniReview Series have been published in FEBS J (www.febsjournal.org):

1st MiniReview Series:Proteoglycans in health and disease: emerging concepts and future directions
Coordinated by Renato V. Iozzo and Nikos Karamanos, http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07796.x/pdf


1. - Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans
Renato V. Iozzo and Liliana Schaefer http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07797.x/pdf

2. - Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis
Uri Barash, Victoria Cohen-Kaplan, Ilana Dowek, Ralph D. Sanderson, Neta Ilan and Israel Vlodavsky

3. - Proteoglycans in health and disease: the multiple roles of syndecan shedding
Tina Manon-Jensen, Yoshifumi Itoh and John R. Couchman

4. - Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting
Achilleas D. Theocharis, Spyridon S. Skandalis, George N. Tzanakakis and Nikos K. Karamanos


2nd MiniReview SeriesMetalloproteinases in health and disease: challenges and the future prospects

Coordinated by Hideaki Nagase and Nikos Karamanos, http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07917.x/pdf



1. Regulation of matrix metalloproteinase activity in health and disease

Elin Hadler-Olsen, Bodil Fadnes, Ingebrigt Sylte, Lars Uhlin-Hansen and Jan-Olof Winberg, http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07920.x/pdf

2. Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

Chrisostomi Gialeli, Achilleas D. Theocharis and Nikos K. Karamanos, http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07919.x/pdf

3. Localizing matrix metalloproteinase activities in the pericellular environment

Gillian Murphy and Hideaki Nagase, http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2010.07918.x/pdf


3rd MiniReview Series: Regulatory roles of hyaluronan in health and disease

Coordinated by Vincent Hascall and Nikos Karamanos, 277 (9) 2011 1411-1443

For more details see the attachment

Download this file (FEBSJournalSeriesonHyaluronan2011.pdf)FEBSJournalSeriesonHyaluronan2011.pdf[ ]145 kB